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Objective  The golden color of  Staphylococcus aureus  is due to the synthesis of carotenoid pigments. In Gram-negative bacteria, Hfq is a global posttranscriptional regulator, but its function in  S. aureus  remains obscure. The absence of Hfq in  S. aureus  was reported to correlate with production of carotenoid pigment leading to the conclusion that Hfq was a negative regulator of the yellow color. However, we reported the construction of  hfq  mutants in several  S. aureus  strains and never noticed any color change; we therefore revisited the question of Hfq implication in  S. aureus  pigmentation.    Results  The absence or accumulation of Hfq does not affect  S. aureus  pigmentation.

Staphylococcus aureus pigmentation is not controlled by Hfq