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Objective  The objective of this study was to determine the prevalence of clarithromycin-resistant  Helicobacter pylori  in asymptomatic children in a rural community of Cajamarca (northern Peru).    Results   Helicobacter pylori  was detected in 17.2% (49/285) of the samples. Unboiled water consumption the most frequent associated factor in patients with positive PCR for  H. pylori  infection (93.9%). Clarithromycin resistant mutations were found in 79.6% (39/49) of the positive samples for  H. pylori . The most frequent mutation was A2142G (46.9%), followed by the double-mutation A2142G–A2143G (28.6%).

Highly clarithromycin-resistant Helicobacter pylori infection in asymptomatic children from a rural community of Cajamarca-Peru