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Background  The aim of this study is to examine knowledge and attitude as facilitators and barriers to the acceptance of HPV vaccination for adolescent girls by mothers and adolescent girls.    Methods  A cross-sectional survey conducted in Hong Kong in January 2010. Adolescent girls aged 12–18, together with their mothers, were recruited to complete two separate questionnaires with similar questions.    Results  A total of 170 mother–adolescent girl dyads were recruited. When the daughters and mothers were compared, the mothers were found to be more aware of “the risk of becoming infected with HPV through early sexual intercourse,” while more daughters than mothers knew that “the HPV virus cannot be cured with antibiotics.” Significantly more daughters perceived that they had a “chance of being infected with HPV and getting cervical cancer without the vaccine,” while more mothers were concerned that “vaccinating for HPV will cause a girl to be stigmatized as promiscuous” and thought that their “adolescent daughters are too young to receive the HPV vaccine.” The major predictive factor for the acceptance of the HPV vaccine among mothers was “The HPV vaccine is safe” (OR = 10.126, 95% CI 2.47–41.54). Among daughters who accepted the vaccine, the predictive factor was “The HPV vaccine can prevent most HPV infections” (OR = 6.274, 95% CI 1.93–20.42).    Conclusions  The findings provide healthcare professionals with a better understanding of the differences between mothers and adolescent girls in knowledge, attitude, and potential factors associated with acceptance of the HPV vaccine. Health professionals should promote the early prevention of HPV infection and eliminate the stigma surrounding HPV vaccination to increase its acceptance. The government should provide financial support for adolescent girls to receive the vaccination in school.

bmc research notes

Facilitators and barriers to the acceptance of human papillomavirus (HPV) vaccination among adolescent girls: a comparison between mothers and their adolescent daughters in Hong Kong