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Background  The emergence of bacterial infections including those associated with  Staphylococcus aureus  causes a benefit of interest to medicinal plants as an effective means of control. The present study was designed to investigate the activities of 12 selected Cameroonian medicinal plants against  S. aureus  isolates.    Methods  The plant extracts were prepared by maceration in methanol at laboratory temperature. Qualitative phytochemical analysis was performed by chemical reaction methods. The broth microdilution method was used to evaluate the activities of plant extracts against 11  S. aureus  clinical isolates.    Results   Dacryodes edulis  was found to have significant antibacterial activity on all the  S. aureus  isolates (MIC = 64–256 µg/ml).  Occimum gratissimum  revealed significant inhibitory activity on 9 of the 11 isolates while  Commelina erecta  and  Spilanthes filicaulis  revealed similar results on 6 of the 11 clinical isolates.    Conclusion  The present findings showed that  D. eduli, O. gratissimum,  C. erecta  and  S. filicaulis  possess interesting inhibitory properties against  S. aureus  species. These plants could therefore be good candidates to overcome infectious diseases associated with these microorganisms.

Anti-Staphylococcus aureus activity of methanol extracts of 12 plants used in Cameroonian folk medicine