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Background  Several studies described the phytochemical constituents of plants in relation with the free radical scavenging property and inhibition of lipid peroxidation. This study investigated the in vitro antioxidant property, and the protective effects of ethanolic and aqueous ethanol extract of the leaves and barks of  Afrostyrax lepidophyllus  (Huaceae) against ion mediated oxidative damages.    Methods  Four extracts (ethanol and aqueous-ethanol) from the leaves and barks of  A. lepidophyllus  were used in this study. The total phenols content, the antiradical and antioxidant properties were determined using standard colorimetric methods.    Results  The plant extracts had a significant scavenging potential on the 2,2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl (OH), nitrite oxide (NO) and 2,2-azinobis (3-ethylbenzthiazoline)-6-sulfonic acid (ABTS) radicals with the IC 50  varied between 47 and 200 µg/mL depending on the part of plant and the type of extract. The ethanol extract of  A. lepidophyllus  bark (GEE) showed the highest polyphenolic (35.33 ± 0.29) and flavonoid (12.00 ± 0.14) content. All the tested extracts demonstrated a high protective potential with the increased of superoxide dismutase, catalase and peroxidase activities.    Conclusion   Afrostyrax lepidophyllus  extracts exhibited higher antioxidant potential and significant protective potential on liver enzymes.    Electronic supplementary material  The online version of this article (doi:10.1186/s13104-015-1304-8) contains supplementary material, which is available to authorized users.

bmc research notes

Afrostyrax lepidophyllus extracts exhibit in vitro free radical scavenging, antioxidant potential and protective properties against liver enzymes ion mediated oxidative damage