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Background  This study is a collaboration between Macquarie University researchers and the Yaegl Aboriginal Community of northern NSW, Australia to investigate the antimicrobial potential of plants used in the topical treatment of wounds, sores and skin infections. Based on previously documented medicinal applications, aqueous and aqueous ethanolic extracts of  Alocasia brisbanensis ,  Canavalia rosea ,  Corymbia intermedia ,  Hibbertia scandens ,  Ipomoea brasiliensis ,  Lophostemon suaveolens  and  Syncarpia glomulifera  and the aqueous extracts of  Smilax australis  and  Smilax glyciphylla  were tested against common wound pathogens, including antibiotic resistant bacterial strains.    Methods  Plant material was prepared as aqueous extractions modelled on customary preparations and using 80% aqueous ethanol. Extracts were assayed against a selection of clinically relevant Gram positive ( Streptococcus pyogenes  and sensitive and resistant strains of  Staphylococcus aureus ) and Gram negative ( Pseudomonas aeruginosa ,  Escherichia coli  and  Salmonella typhimurium ) bacteria and a fungus ( Candida albicans ) using disc diffusion and MTT microdilution methods. Viability of treated microorganisms was determined by subculturing from microdilution assays.    Results  The extracts of  Corymbia intermedia ,  Lophostemon suaveolens  and  Syncarpia glomulifera  had promising levels of antimicrobial activity (MIC 31–1,000 µg/mL) against both antibiotic sensitive and resistant  Staphylococcus aureus  as well as the fungus  Candida albicans  (clinical isolate).    Conclusion  Aqueous and 80% aqueous ethanolic extracts of  Lophostemon suaveolens ,  Corymbia intermedia  and  Syncarpia glomulifera  exhibited promising levels of antimicrobial activity against a range of both antibiotic sensitive and resistant strains of microorganisms. This is the first report of antimicrobial activities for  C. intermedia  and  L. suaveolens  and the leaves of  S. glomulifera . This study demonstrates the value of customary knowledge in the identification of new sources of antimicrobial treatments.    Electronic supplementary material  The online version of this article (doi:10.1186/s13104-015-1258-x) contains supplementary material, which is available to authorized users.

Antimicrobial activity of customary medicinal plants of the Yaegl Aboriginal community of northern New South Wales, Australia: a preliminary study