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Background    Bacillus cereus  is well known as a gastrointestinal pathogen that causes food-borne illness. In the present study, we sequenced the complete genome of  B. cereus  FORC_013 isolated from fried eel in South Korea. To extend our understanding of the genomic characteristics of FORC_013, we conducted a comparative analysis with the published genomes of other  B. cereus  strains.    Results  We fully assembled the single circular chromosome (5,418,913 bp) and one plasmid (259,749 bp); 5511 open reading frames (ORFs) and 283 ORFs were predicted for the chromosome and plasmid, respectively. Moreover, we detected that the enterotoxin (NHE, HBL, CytK) induces food-borne illness with diarrheal symptom, and that the pleiotropic regulator, along with other virulence factors, plays a role in surviving and biofilm formation. Through comparative analysis using the complete genome sequence of  B. cereus  FORC_013, we identified both positively selected genes related to virulence regulation and 224 strain-specific genes of FORC_013.    Conclusions  Through genome analysis of  B. cereus  FORC_013, we identified multiple virulence factors that may contribute to pathogenicity. These results will provide insight into further studies regarding  B. cereus  pathogenesis mechanism at the genomic level.    Electronic supplementary material  The online version of this article (doi:10.1186/s13099-017-0175-z) contains supplementary material, which is available to authorized users.

Comparative genomic analysis reveals genetic features related to the virulence of Bacillus cereus FORC_013