English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background   Cryptosporidium  spp. are worldwide protozoan parasites which include species that can lead to cryptosporidiosis in humans. Different animal species can serve as reservoirs and sources of dissemination of the disease, such as rodent species due their potential in transmitting zoonotic pathogens to humans and other animals. In the Canary Islands (Spain),  Cryptosporidium parvum  and  Cryptosporidium hominis  have been identified in patients with diarrhea. However, the occurrence of  Cryptosporidium  spp. in possible reservoirs in this archipelago remains unclear. Considering the zoonotic potential of these protozoans, the aim of the present study was to determine the presence of  Cryptosporidium  spp. in peridomestic wild rodents and the possible role of these mammals as a source of transmission of these protozoans in Canary Islands.    Methods  A total of 179 rodents belonging to  Rattus rattus  and  Mus musculus domesticus  from four Canary Islands, La Palma, El Hierro, Tenerife and Lanzarote, were analyzed. Feces were screened for  Cryptosporidium  spp. by nested PCR of the  18S  ribosomal RNA fragment and the sequences used for phylogenetic analyses.    Results   Cryptosporidium  spp. were found widely distributed with an overall prevalence of 12.30% in rodents (13.86% for  R. rattus  and 10.25% for  M. m. domesticus ). The overall prevalence by island was 19.60% for Tenerife, 7.14% for La Palma, 5.71% for El Hierro and 0% for Lanzarote.  Cryptosporidium tyzzeri ,  Cryptosporidium meleagridis ,  Cryptosporidium muris  and  Cryptosporidium  sp. rat genotype I and II/III were successfully identified, in addition to two unidentified  Cryptosporidium  genotypes.    Conclusions  This study contributes to the knowledge of the biodiversity and distribution of  Cryptosporidium  spp. in wild rodents from the Canary Islands, highlighting the presence of three zoonotic species,  C. tyzzeri ,  C. meleagridis  and  C. muris , being the first detection of these three species in wild rodents in the Canary Islands and the first report of  C. meleagridis  in  R. rattus . Given the results obtained in our study, future studies in non-sampled areas are required to better understand the epidemiology of these protozoans in wild rodents in the archipelago.

Diversity of Cryptosporidium spp. in wild rodents from the Canary Islands, Spain