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Background  The susceptibility of  Anopheles albimanus  and  An. pseudopunctipennis  to local  Plasmodium vivax  has been associated in southern Mexico with two ookinete surface proteins (Pvs25/28) polymorphism. Perhaps parasite population selection (i.e. adaptation to local vectors) contributes to this phenomenon. It is also possible that certain molecular interactions exist between  P. vivax  and each mosquito species independently of geographical origin. This study aimed to explore the susceptibility of  An. albimanus  and  An. pseudopunctipennis  (collected from different geographical sites) to  P. vivax  cspVk/Pvs25-130 haplotypes from southern Mexico.    Results  Of the 120  P. vivax -infected blood samples used to simultaneously feed  An. albimanus  and  An. pseudopunctipennis  mosquitoes originating from various geographical sites, 80 produced at least one infected mosquito species. Three parasite haplotypes were identified in infected blood: Vk210/Pvs25-A (12.5%), Vk210/Pvs25-B (20%) and Vk247/Pvs25-B (67.5%). Two parameters (the proportion of infected mosquitoes and number of oocysts/mosquito) showed a similar pattern for each mosquito species (independently of geographical origin). For  An. albimanus  mosquitoes (from the Pacific coast, Mexican gulf and Lacandon Forest lowlands), these two parameters were higher in specimens infected with  P. vivax  Vk210/Pvs25-A  versus  Vk210/Pvs25-B or Vk247/Pvs25-B ( P  < 0.001). For  An. pseudopunctipennis  mosquitoes (from the Pacific coast, northeast Mexico and east Guatemala foothills), the same two parameters were higher in specimens infected with Vk247/Pvs25-B or Vk210/Pvs25-B  versus  Vk210/Pvs25-A ( P  < 0.001). Higher infection rates were caused by Vk247/Pvs25-B than Vk210/Pvs25-B parasites in  An. pseudopunctipennis  ( P  = 0.011 )  and  An. albimanus  ( P  = 0.001). The greatest parasitaemia, gametocytaemia and microgamete formation was observed in Vk247/Pvs25-B infected blood, and each of these parameters correlated with each other and with the number of oocysts in  An. pseudopunctipennis  from the sympatric colony.    Conclusions   Plasmodium vivax  Vk247/Pvs25-B infections were the most prevalent, likely due to the higher parasitaemia produced in the susceptible vector (especially  An. pseudopunctipennis ). The analysis of mosquito-parasite interactions indicate that  An. pseudopunctipennis  and  An. albimanus  each have a unique pattern of transmitting genetic variants of  P. vivax , and this is not dependent on geographical origin. The present findings highlight the importance of parasite genotyping to understand transmission dynamics and vectorial participation.    Electronic supplementary material  The online version of this article (10.1186/s13071-019-3331-0) contains supplementary material, which is available to authorized users.

parasites and vectors

Plasmodium vivax CSP-Pvs25 variants from southern Mexico produce distinct patterns of infectivity for Anopheles albimanus versus An. pseudopunctipennis, in each case independent of geographical origin