English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background  Rift Valley fever is a mosquito-borne zoonotic disease that affects domestic ruminants and humans. Culex flavivirus is an insect-specific flavivirus that naturally exists in field mosquito populations. The influence of Culex flavivirus on Rift Valley fever phlebovirus (RVFV) vector competence of  Culex pipiens  has not been investigated.    Methods  Culex flavivirus infection in a  Cx. pipiens  colony was studied by Culex flavivirus oral feeding and intrathoracical inoculation. Similarly, vector competence of  Cx. pipiens  infected with Culex flavivirus was evaluated for RVFV. Infection, dissemination, transmission rates and transmission efficiency of Culex flavivirus-infected and non-infected  Cx. pipiens  artificially fed with RVFV infected blood were assessed.    Results  Culex flavivirus was able to infect  Cx. pipiens  after intrathoracically inoculation in  Cx. pipiens  mosquitos but not after Culex flavivirus oral feeding. Culex flavivirus did not affect RVFV infection, dissemination and transmission in  Cx. pipiens  mosquitoes. RVFV could be detected from saliva of both the Culex flavivirus-positive and negative  Cx. pipiens  females without significant differences. Moreover, RVFV did not interfere with the Culex flavivirus infection in  Cx. pipiens  mosquitoes.    Conclusions  Culex flavivirus infected and non-infected  Cx. pipiens  transmit RVFV. Culex flavivirus existing in field-collected  Cx. pipiens  populations does not affect their vector competence for RVFV. Culex flavivirus may not be an efficient tool for RVFV control in mosquitoes.

Culex flavivirus infection in a Culex pipiens mosquito colony and its effects on vector competence for Rift Valley fever phlebovirus