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Background  The filamentous fungus  Trichoderma reesei  (anamorph of  Hypocrea jecorina ) displays increased cellulase expression while growing on inducers such as lactose or cellulose. However, the mechanism of cellulase induction in  T. reesei  is not yet completely characterized. Here, a protein annotated as β-glucosidase (BGL3I) was found to be involved in cellulase induction in  T. reesei . The effects of BGL3I on cellulase production have not yet been fully understood.    Results  Deletion of the  bgl3i  gene had no influence on the growth of  T. reesei , but significantly increased its cellulase activities. Deletion of  bgl3i  also resulted in decreased extracellular galactosidase activity, but significantly increased transcription of lactose permeases, which might be involved in lactose transport. Furthermore, deletion of  bgl3i  enhanced the transcription levels of intracellular β-glucosidases  cel1a, cel1b  and the regulator  xyr1 , which are all essential for lactose induction in  T. reesei . BGL3I was found to have a relatively high ability to hydrolyze sophorose, which is proposed to be the strongest natural inducer of cellulase synthesis in  T. reesei .    Conclusions  BGL3I may take part in the complex regulating system of cellulase induction. The deletion of  bgl3i  offers a new strategy to improve  T. reesei  strain performance.    Electronic supplementary material  The online version of this article (10.1186/s13068-018-1314-6) contains supplementary material, which is available to authorized users.

The putative β-glucosidase BGL3I regulates cellulase induction in Trichoderma reesei