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Erratum After the publication of this work [1] it has been brought to our attention that the descriptions of the generation of the two simulated datasets were confusing. In the section ‘Benchmarking of methods for individual gene sets’, the first sentence of the second paragraph should specify the number of genes included in the gene set as 100, and it should read: “We compared CoMEt to the other methods on datasets with m = 100 genes and n = 500 samples and with implanted pathways with coverages γ ranging from 0.1 to 1.0.” In the section ‘Benchmarking identification of collections of gene sets’, the first paragraph should specify that genes mutated in fewer than 1% of total samples (that is in fewer than 5 out of 500 samples) were removed from the simulation, and the sixth sentence in this paragraph should read: “Third, we include m = 20,000 genes and remove those genes that are mutated in fewer than 1% of total samples (that is in fewer than 5 out of 500 samples) (Additional file 1: Figure S2).” Additionally, these descriptions are also included in the Additional file 1, section S3, and should read: “We generated two different versions of the simulated datasets, depending on whether we implanted a single or multiple gene sets. We describe the method for generating datasets with multiple implanted gene sets in the main text. For all simulated datasets, we used n = 500, |C| = 5, γC = (0.67, 0.49, 0.29, 0.29, 0.2), and q = 0.0027538462.1 We used μP = (0.5, 0.35, 0.15) for the single pathway simulations.”

Erratum to: CoMEt: a statistical approach to identify combinations of mutually exclusive alterations in cancer