English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

s from the 23rd Italian congress of Cystic Fibrosis and the 13th National congress of Cystic Fibrosis Italian Society Naples, Italy. 22-25 November 2017 Published: 16 January 2018 S1 Effects of diet on cystic fibrosis microbiome Annamaria Bevivino (annamaria.bevivino@enea.it) ENEA Casaccia Research Center, Sustainable Territorial and Production Systems Department, Rome, Italy Italian Journal of Pediatrics 2018, 44(Suppl 1):S1 The human body contains complex communities of microorganisms that play an important role in human health. In the last decade, next-generation sequencing (NGS) was employed to decipher the structure and composition of the human microbiome, defined as the totality of microbes, their genomes and interactions in a defined environment. Cystic Fibrosis (CF) disease affects the function of a number of organs, principally the lungs, but also the gastrointestinal tract [1]. An increasing number of studies have revealed a cross-talk between the two compartiments as exemplified by intestinal complications during respiratory disease and vice versa. Although so far mechanisms through which the lung could influence the gut environment are unclear, the existence of the gut–lung axis could open up new possibilities for therapeutic approaches to respiratory diseases. A growing body of evidence suggests that the gastrointestinal (GI) microbiome in people with CF is altered. These dysbioses contribute to disease manifestations in many organs, both within and beyond the GI tract [2]. In this lecture, I highlight how changes in the intestinal microenvironment, with a particular focus on the intestinal microbiota, impact upon respiratory disease. Together with reported benefits for respiratory exacerbations, such as a reduced rate of pulmonary exacerbations and upper respiratory tract infections in patients with CF, the administration of probiotcs may globally modify the GI microbiome, thus promoting bacterial communities that modulate host immune responses [3]. Observations from clinical trials of probiotics in CF patient revealed the probiotics can ameliorate the dysbiosis of CF, reducing the proteobacterial populations in the gut microbiota, as well as decreasing gut inflammation and the number of pulmonary exacerbations.

Abstracts from the 23rd Italian congress of Cystic Fibrosis and the 13th National congress of Cystic Fibrosis Italian Society