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Background  The aim of this study was to identify the diagnostic role of plasma calprotectin value for a distinction of presence acute appendicitis and the indifference of uncomplicated from complicated acute appendicitis.    Methods  Plasma calprotectin, white blood cell and C-reactive protein values of 89 patients, who have undergone laparoscopic appendectomy between January 2013 and May 2013 were evaluated.    Results  Calprotectin was 91 ng/mL (range 45–538) for acute appendicitis and 47 ng/ml (range 28–205) for the control group. There was a positive, statistically significant relation between calprotectin and C-reactive protein values ( r  = 0. 292  p  = 0. 001, respectively). There was no statistically significant difference was determined between calprotectin and white blood cell values ( r  = 0. 142  p  = 0. 187, respectively). CRP and Cal values were significantly higher in patients with a complicated AA group than in those with uncomplicated AA ( p  = 0. 014,  p  = 0. 0001, respectively) whereas white blood cell counts did not differ significantly between two groups ( p  = 0. 164).    Conclusion  Plasma calprotectin levels were increased in patients with acute appendicitis and should use in a distinction of uncomplicated from complicated acute appendicitis patients.

Plasma calprotectin level: usage in distinction of uncomplicated from complicated acute appendicitis