English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background  The value of apparent diffusion coefficient (ADC) values and quantitative parameters (Ktrans, Kep, Ve) in detecting prognostic factor at 3.0 Tesla remains unclear, especially in predicting prognosis of breast cancer.    Methods  A total of 151 patients with IDC underwent breast DCE-MRI and DWI-MRI at 3.0 Tesla following surgery. The ADC values were acquired with  b  values of 0 and 1000 s/mm 2 . The relationship between ADC values or DCE-MRI quantitative parameters and size, histologic grade (HG), lymph node metastasis (LNM), ER, PR, and Ki67 was evaluated. The predictive values of ADC, Ktrans, Kep, and Ve to prognosis of IDC were assessed.    Results  ADC value was positively related to size ( P  = 0.04) and HER2 ( P  = 0.046) expression and negatively related to ER ( P  = 0.012) and PR ( P  < 0.001) expression. Ktrans value has positive correlation with size ( P  < 0.001), HG ( P  < 0.001), LNM ( P  < 0.001), HER2 ( P  = 0.007), and Ki67 ( P  < 0.001) expression and negative correlation with ER ( P  < 0.001) and PR ( P  < 0.001) expression. Kep value was positively related to size ( P  < 0.001) and negatively related to ER ( P  < 0.001) and PR ( P  < 0.001) expression. Ve value was negatively related to HER2 expression ( P  = 0.004). The Cox hazard ratio (HR) of ADC, Ktrans, Kep, and Ve values on survival was 5.26 ( P  = 0.093), 1.081 ( P  = 0.002), 1.006 ( P  = 0.941), and 0.883 ( P  = 0.926), respectively.    Conclusions  Ktrans value was a best predictive indicator of HG, LNM, ER, PR, and Ki67 expression, and ADC value was the best predictive indicator of HER2. Preoperative use of the 3.0 Tesla could provide important information to determine the optimal treatment plan.

Role of perfusion parameters on DCE-MRI and ADC values on DWMRI for invasive ductal carcinoma at 3.0 Tesla