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Background  The overwhelming number of potentially toxic chemicals in consumer products and in our daily environment makes it unrealistic to carry out in-depth analyses of each product with the objective of banning and eliminating toxic chemicals from our environment.    Objectives  To present the challenges that environmental toxicology and epidemiology are currently facing in the context of ubiquitous chemical pollution.    Discussion  We propose a realistic and pragmatic approach to this Herculean problem.

Learning from Sisyphus: time to rethink our current, ineffective strategy on neurodevelopmental environmental toxicants