English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background   Helicobacter pylori  antibody titters fall very slowly even after successful treatment. Therefore, tests detecting  H. pylori  antibody lack specificity and sensitivity. On the other hand,  H. pylori  stool antigen tests are reported as an alternative assay because of their reliability and simplicity. However, the comparative performance of  H. pylori  stool antigen tests for detecting the presence of the bacterium in clinical specimens in the study area is not assessed. Therefore, in this study we evaluated the performance of SD BIOLINE  H. pylori  Ag rapid test with reference to the commercially available EZ- STEP ELISA and SD BIOLINE  H. pylori  Ag ELISA tests.    Methods  Stool samples were collected to analyse the diagnostic performance of SD BIOLINE  H. pylori  Ag rapid test kit using SD  H. pylori  Ag ELISA kit and EZ- STEP ELISA tests as a gold standard. Serum samples were also collected from each patient to test for the presence of  H. pylori  antibodies using dBest  H. pylori  Test Disk. Sensitivity, specificity, predictive values and kappa value are assessed.  P  values < 0.05 were taken statistically significant.    Results  Stool and serum samples were collected from 201 dyspeptic patients and analysed. The sensitivity, specificity, positive and negative predictive values of the SD BIOLINE  H. pylori  Ag rapid test were: 95.6% (95% CI, 88.8–98.8), 92.5% (95%CI, 89–94.1%), 86.7% (95% CI, 80.5–89.6), and 97.6% (95% CI, 993.9–99.3) respectively.    Conclusion  The performance of SD BIOLINE  H. pylori  Ag rapid test was better than the currently available antibody test in study area. Therefore, the SD BIOLINE Ag rapid stool test could replace and be used to diagnose active  H. pylori  infection before the commencement of therapy among dyspeptic patients.

Evaluation of SD BIOLINE H. pylori Ag rapid test against double ELISA with SD H. pylori Ag ELISA and EZ-STEP H. pylori Ag ELISA tests