English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background  Clinical history-taking can be employed as a standardized approach to elucidate the use of herbal medicines and their linked suspected adverse drug reactions (ADRs) among hospitalized patients. We sought to identify herbal medicines nominated by Ugandan inpatients; compare nomination rates by ward and gender; confirm the herbs’ known pharmacological properties from published literature; and identify ADRs linked to pre-admission use of herbal medicines.    Methods  Prospective cohort of consented adult inpatients designed to assess medication use and ADRs on one gynaecological and three medical wards of 1790-bed Mulago National Referral Hospital. Baseline and follow-up data were obtained on patients’ characteristics, including pre-admission use of herbal medicines.    Results  Fourteen percent (26/191) of females in Gynaecology nominated at least one specific herbal medicine compared with 20 % (114/571) of inpatients on medical wards [20 % (69/343) of females; 20 % (45/228) of males]. Frequent nominations were  Persea americana  (30), Mumbwa/multiple-herb clay rods (23),  Aloe barbadensis  (22),  Beta vulgaris  (12),  Vernonia amygdalina  (11),  Commelina africana  (7),  Bidens pilosa  (7),  Hoslundia opposita  (6),  Mangifera indica  (4), and  Dicliptera laxata  (4). Four inpatients experienced 10 suspected ADRs linked to pre-admission herbal medicine use including  Commelina africana  (4), multiple-herb-mumbwa (1), or unspecified local-herbs (5): three ADR-cases were abortion-related and one kidney-related.    Conclusions  The named herbal medicines and their nomination rates generally differed by specialized ward, probably guided by local folklore knowledge of their use. Clinical elicitation from inpatients can generate valuable safety data on herbal medicine use. However, larger routine studies might increase the utility of our method to assess herbal medicine use and detect herb-linked ADRs. Future studies should take testable samples of ADR-implicated herbal medicines for further analysis.    Electronic supplementary material  The online version of this article (doi:10.1186/s12906-016-1125-x) contains supplementary material, which is available to authorized users.

Herbal medicine use and linked suspected adverse drug reactions in a prospective cohort of Ugandan inpatients