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Background  Many people, although they may recognise the positive effects of exercise, do not exercise regularly owing to lack of time. This study aimed to investigate the effects of prolonged single-session exercise and multiple short sessions of exercise on the risk of metabolic syndrome and the atherogenic index in middle-aged obese women.    Methods  Thirty-six participants were divided into the single-session group, multiple-session group, and control group. The single-session group engaged in one session of treadmill exercise for 30 min a day; the multiple-session group had three sessions of 10 min a day. Both groups exercised 3 days/week for 12 weeks. The control group did not perform any exercise.    Results  The single-session group showed decreases in weight (0.97 kg [95% C.I. = 0.09–1.83],  p  < .05), body mass index (0.43 kg/m 2  [95% C.I. = 0.03–0.81],  p  < .05), and fat mass (1.65 kg, [95% C.I. = 0.78–2.51],  p  < .01). Systolic blood pressure dropped in the single-session group (6.66 mmHg, [95% C.I. = 1.44–11.88],  p  < .05), and diastolic blood pressure dropped in the multiple-session group (3.38 mmHg, [95% C.I. = 1.44–5.88],  p  < .01). High-density lipoprotein cholesterol rose in the single-session group (4.08 mg/dL, [95% C.I. = −8.08–(−)0.07],  p  < .05) and dropped in the control group (10.75 mg/dL [95% C.I. = 1.95–19.54],  p  < .01). According to post hoc analysis, high-density lipoprotein cholesterol increased more in the single-session group than the control group (95% C.I. = 0.61–21.88,  p  < .05). Glucose levels decreased in both the single-session group (16 mg/dL [95% C.I. = 5.64–26.35],  p  < .01) and the multiple-session group (12.16 mg/dL, [95% C.I. = 2.18–22.14],  p  < .05). Waist circumference decreased in the single-session group (2.65 cm [95% C.I. = 1.46–3.83],  p  < .001) and multiple-session group (2.04 cm, [95% C.I. = 1.51–2.73],  p  < .001). Low-density lipoprotein cholesterol levels rose in both the multiple-session group (−15.79 mg/dL [95% C.I. = −34.24–(−)3.78],  p  < .05) and the control group (−22.94 mg/dL [95% C.I. = −44.63–(−)1.24],  p  < .05). The atherogenic index increased in the control group (−1.06 [95% C.I. = −1.69–(−)0.41],  p  < .01).    Conclusions  The findings indicate that prolonged exercise is superior to multiple short sessions for improving the risk of metabolic syndrome and the atherogenic index in middle-aged obese women. However, multiple short sessions can be recommended as an alternative to prolonged exercise when the goal is to decrease blood glucose or waist circumference.

bmc women's health

Effects of prolonged exercise versus multiple short exercise sessions on risk for metabolic syndrome and the atherogenic index in middle-aged obese women: a randomised controlled trial