English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background Chemical Plaque control by antimicrobial agent application can defend the teeth against caries.  S. mutans  is considered the main etiologic factor for caries. This was an in vitro study to compare between the efficacy of chlorhexidine diaceteate varnish, and an organoselenium sealant, to prevent  S. mutans  biofilm formation on human teeth. Methods Fourty five premolars extracted for orthodontic purposes were randomly divided into 3 groups of 15 teeth each. One control group and two test groups, chlorhexidine diaceteate varnish and an organoselenium sealant. The teeth were autoclaved before  S. mutans  biofilm was induced on to each in their respective groups. The reading T1 was taken for each tooth to assess the number of  S. mutans  attached in order to compare for differences in surface area among the 3 groups. The respective test materials were applied onto the teeth and biofilm induced onto them in their respective groups. The reading T2 was taken for the 2 test groups. The 3 groups were then subjected to aging for a period equivalent to 5 months before the biofilm was induced to take the reading T3 for the number of  S. mutans . We used vortexing of the teeth to disrupt the biofilm at time points T1, T2 and T3.  S. mutans  count was then done using PCR. Results There were significantly lower  S. mutans  counts in the control group as compared to the chlorhexidine diacetate group at T3.There were no other statistically significant differences found. Conclusion Both organoselenium and Chlorhexidine diacetate do not inhibit  S. mutans  biofilm attachment onto the teeth.

Chlorhexidine versus organoselenium for inhibition of S. mutans biofilm, an in vitro study