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Background  The aim of this study was to determine in vitro the bactericidal potential of 38% silver diamine fluoride (SDF) alone, potassium iodide (PI) alone, and the two in combination (SDF + PI) against three bacterial species commonly found in root canal samples ( Enterococcus faecalis ,  Actinomyces naeslundii  and  Parvimonas micra ).Methods  The potential bactericidal rates for SDF, PI and SDF + PI against  E. faecalis ,  A. naeslundii  and  P. micra  were calculated as reduction of bacteria colony forming units.    Results  The bactericidal potential of SDF was at 99.97–100% against  E. faecalis  and 100% against  A. naeslundii  and  P. micra . SDF + PI showed a 100% bactericidal effect against  P. micra , 99.89–99.98% against  E. faecalis  and 99.98–100% against  A. naeslundii . The bactericidal effect of PI was 99.51–99.98% against  E. faecalis , 99.27–99.95% against  A. naeslundii  and 99.93–100% against  P. micra . The differences between controls and bacteria exposed to the antibacterial agents were statistically significant ( p  < 0.05).    Conclusions  SDF had an effective bactericidal effect against the examined bacteria. However, the limitations of this in vitro study do not allow a recommendation of the employment of these solutions as root canal irrigants. Additional investigations are necessary to assess their endodontic clinical applicability.

Antibacterial effect of silver diamine fluoride and potassium iodide against E. faecalis, A. naeslundii and P. micra