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Background  Noninvasive estimation of the actual systolic pulmonary artery pressure measured via right-sided heart catheterization (sPAP RHC ) is vital for the management of pulmonary hypertension, including chronic thromboembolic pulmonary hypertension (CTEPH). Evaluation related to the interventricular septum (IVS) is generally performed with only visual assessment and has been rarely assessed quantitatively in the field of echocardiography. Thus, this study aimed to investigate the utility of echocardiographic IVS curvature to estimate sPAP RHC  in patients with CTEPH.    Methods  Medical records of 72 patients with CTEPH were studied retrospectively. We estimated sPAP RHC  using echocardiographic IVS curvature (esPAP curv ) and left ventricular eccentricity index (esPAP LVEI ), and compared their ability to predict sPAP RHC  with estimated sPAP RHC  using tricuspid regurgitant pressure gradient (esPAP TRPG ).    Results  IVS curvature and LVEI were significantly correlated with sPAP RHC  (r = − 0.52 and r = 0.49, respectively). Moreover, the IVS curvature was effective in estimating the sPAP RHC  of patients with trivial tricuspid regurgitation (r = − 0.56) and in determining patients with sPAP RHC  ≥ 70 mmHg with higher sensitivity (77.0%) compared to those with esPAP TRPG  and esPAP LVEI .    Conclusion  Our results indicate that the echocardiographic IVS curvature could be a useful additional tool for estimating sPAP RHC  in CTEPH patients for whom accurate estimation of sPAP RHC  using tricuspid regurgitant pressure gradient is challenging.    Supplementary Information  The online version contains supplementary material available at 10.1186/s12890-021-01683-4.

bmc pulmonary medicine

Interventricular septal curvature as an additional echocardiographic parameter for evaluating chronic thromboembolic pulmonary hypertension: a single-center retrospective study