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Background  The aim of this study was to investigate the relationship between dynamic hyperinflation and daily physical activity (DPA) in adults with cystic fibrosis (CF).    Methods  Thirty-four clinically stable CF were studied. All patients undertook incremental cardiopulmonary exercise testing (CPET). CPET-related measurements included: oxygen uptake (V’O 2 ), carbon dioxide production (V’CO 2 ), ventilatory profile, work rate (W), inspiratory capacity (IC), end-expiratory lung volume (EELV). PA was assessed using the accelerometer SenseWear Pro3 Armband.    Results  Exercise tolerance was reduced in most of patients and the mean V’O 2,peak  value was 75.2% of predicted (28.5 ± 4.8 ml/min/kg). Seventy % of patients responded to CPET with dynamic hyperinflation. Higher incidence of dynamic hyperinflation was found in CF males compared to CF females ( p  = 0.026). Patients who developed dynamic hyperinflation during CPET had higher vigorous PA ( p  = 0.01) and more total energy expenditure ( p  = 0.006) than patients who did not. EELVΔ was related to activities requiring vigorous intensity and total energy expenditure ( R  = 0.46,  p  = 0.001;  R  = 0.57,  p  <  0.001).    Conclusions  In adults with CF and mild to moderate lung impairment, DPA might not be limited by dynamic hyperinflation.    Electronic supplementary material  The online version of this article (10.1186/s12890-018-0623-7) contains supplementary material, which is available to authorized users.

Is daily physical activity affected by dynamic hyperinflation in adults with cystic fibrosis?