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Background  Finding effective intervention strategies to combat rising obesity levels could significantly reduce the burden that obesity and associated non-communicable diseases places on both individuals and the National Health Service.    Methods  In this parallel randomised-controlled trial, 76 participants who are overweight or obese (50 female) were given free access to a fitness centre for the duration of the 12-week intervention and randomised to one of three interventions. The commercial intervention, the Healthy Weight Programme, (HWP,  n  = 25, 10/15 men/women) consisted of twelve 1-h nutrition coaching sessions with a nutritionist delivered as a mixture of group and 1 to 1 sessions. In addition, twice-weekly exercise sessions (24 in total) were delivered by personal trainers for 12 weeks. The  NHS  intervention ( n  = 25, 8/17 men/women) consisted of following an entirely self-managed 12-week online NHS resource. The  GYM  intervention ( n  = 26, 8/18 men/women) received no guidance or formal intervention. All participants were provided with a gym induction for safety and both the NHS and GYM participants were familiarised with ACSM physical activity guidelines by way of a hand-out.    Results  The overall follow-up rate was 83%. Body mass was significantly reduced at post-intervention in all groups (HWP:  N  = 18, − 5.17 ± 4.22 kg, NHS:  N  = 21–4.19 ± 5.49 kg; GYM:  N  = 24–1.17 ± 3.00 kg;  p  < 0.001) with greater reductions observed in HWP and NHS groups compared to GYM ( p  < 0.05). Out with body mass and BMI, there were no additional statistically significant time x intervention interaction effects.    Conclusions  This is the first study to evaluate the efficacy of both a free online NHS self-help weight-loss tool and a commercial weight loss programme that provides face-to-face nutritional support and supervised exercise. The findings suggest that both interventions are superior to an active control condition with regard to eliciting short-term weight-loss.    Trial registration  ISRCTN Registry -  ISRCTN31489026 . Prospectively registered: 27/07/16.

bmc public health

Evaluating differences in the clinical impact of a free online weight loss programme, a resource-intensive commercial weight loss programme and an active control condition: a parallel randomised controlled trial