English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Background  It has been recognized that alternate day calorie restriction (ADCR) or exercise has positive effects on cardio-metabolic risk factors. It is unclear whether the combined effect of ADCR and exercise (aerobic + resistance training) influences risk. We investigated effects of an 8-week ADCR and exercise program (aerobic + resistance training) on cardio-metabolic risk factors in overweight and obese adults.    Methods  This study randomized 45 overweight or obese but healthy adults (F = 26, M = 19; aged about 32 to 40 years) into 4 groups: ADCR ( n  = 13), exercise ( n  = 10), exercise plus ADCR ( n  = 12), and control (n = 10) for 8 weeks. Body composition, blood lipids profile, and insulin resistance were measured. The intention to treat (ITT) method was used to analyze all participants that were randomized.    Results  A total of 35 participants completed the trial (78%). Body weight, body mass index, waist circumference, fat mass and percent body fat were reduced in the exercise plus ADCR group (− 3.3 ± 2.4 kg,  p  < 0.01; − 1.3 ± 1.0 kg/m 2 ,  p  < 0.01; − 4.1 ± 3.9 cm,  p  < 0.01; − 2.7 ± 2.0 kg,  p  < 0.01; − 2. 5 ± 2.2%,  p  < 0.01). Insulin, glucose, homeostasis model assessment insulin resistance and triglyceride (− 2.9 ± 4.1 μIU/ml,  p  < 0.05; − 10.9 ± 16.9 mg/dl,  p  < 0.05; − 0.9 ± 1.3,  p  < 0.05; − 43.8 ± 41.9 mg/dl,  p  < 0.01) decreased in the exercise plus ADCR group only.    Conclusions  ADCR and exercise both proved to be beneficial, but the combined intervention was most effective at inducing beneficial changes in body weight, body composition, glucose, insulin, insulin resistance and triglyceride in overweight and obese adults.    Trial registration  ClinicalTrials.gov:  NCT03652532 , Registered August 28, 2018, ‘retrospectively registered’.    Electronic supplementary material  The online version of this article (10.1186/s12889-018-6009-1) contains supplementary material, which is available to authorized users.

bmc public health

Effects of alternate day calorie restriction and exercise on cardio-metabolic risk factors in overweight and obese adults: an exploratory randomized controlled study