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Background  No previous study has explored the interactions between education and lifestyle in relation to obesity. This study hypothesized that education may be obesogenic through its interplay with lifestyle behaviors.    Methods  Data for a nationally representative sample (6937 men and 9333 women) from the Korea National Health and Nutrition Examination Survey (2010–2012) were analyzed. Multivariate logistic regressions were performed for three education levels and six lifestyle behaviors, each of which comprised two groups.    Results  Interactions between education and lifestyle behaviors in relation to obesity were observed for all lifestyle behaviors in women ( p  for interaction <0.001) and for three lifestyle behaviors in men. Education appeared obesogenic for three groups of lifestyle behaviors in men ( p  for trend <0.05), but was protective against obesity for 11 groups in women. Each one-unit increase in education level in men increased the odds of obesity by 1.29-fold among under-reported energy intake groups (95 % confidence interval: 1.16, 1.44).    Conclusions  Education may be a risk factor for obesity through its interplay with lifestyle behaviors. Further research is required to examine these findings in different socio-cultural settings.    Electronic supplementary material  The online version of this article (doi:10.1186/s12889-016-3776-4) contains supplementary material, which is available to authorized users.

Modifying effects of education on the association between lifestyle behaviors and the risk of obesity: evidence from South Korea