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Background  Incomplete aneurysmal occlusion is a common feature of immediate posttreatment angiography. The safety and outcomes of acutely ruptured intracranial aneurysms (RIAs) with incomplete occlusion after stent-assisted coiling (SAC) and no-stent coiling (NSC) have not been well clarified. Progressive occlusion of stents can promote the complete occlusion of intracranial aneurysms (IAs), but it remains to be determined if progressive occlusion in acutely RIAs with incomplete occlusion after coiling may be enhanced by protective stenting. This study aimed to evaluate the safety and outcomes of those aneurysms after SAC and NSC; And to discover whether the stents can promote progressive aneurysm occlusion in such lesions or not.    Methods  We reviewed 199 patients with acutely RIAs underwent endovascular coiling and developed incomplete occlusion in the past seven years. The patients’ clinical and imaging information were recorded and analyzed. Univariate and multivariate analyses were performed to determine the association of recurrence rate with potential risk factors.    Results  SAC group had wider aneurysms neck (3.471 mm vs 2.830 mm,  P  = 0.009) and smaller dome-to-neck ratio (1.536 vs 2.111,  P  = 0.001) than in NSC group. There was no significant difference between the two groups in total procedure-related complications rate (31.7% vs 23.5%,  P =  0.195), procedure-related mortality (6.9% vs 2.0%,  P =  0.170) and modified Rankin Scale (mRS) score at 6-month follow-up ( P  > 0.05). However, SAC group had significantly higher ischemic complications rate (21.8% vs 8.2%,  P  = 0.007) and complete occlusion rate (65.6% vs 48.3%,  P  = 0.020), and lower recurrence rate (15.6% vs 28.1%,  P  = 0.042) than NSC group based on 6-month follow-up angiograms. Additionally, Multivariable analysis showed NSC was an independent risk factor for aneurysm recurrence (Odds Ratio [OR]: 4.061;  P  = 0.018).    Conclusions  Acutely RIAs with incomplete occlusion after SAC is associated with higher complications rate and mortality, but has an acceptable safety profile and similar clinical outcome compared to NSC, as well as gives patients superior angiography outcome by progressive occlusion of stents.

The safety and outcomes of acutely ruptured intracranial aneurysms with incomplete occlusion after coiling: a case-control study