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Background  The study aimed to investigate the predictive value of the quick sequential organ failure assessment (qSOFA) for clinical outcomes in emergency patients with community-acquired pneumonia (CAP).    Methods  A total of 742 CAP cases from the emergency department (ED) were enrolled in this study. The scoring systems including the qSOFA, SOFA and CURB-65 (confusion, urea, respiratory rate, blood pressure and age) were used to predict the prognostic outcomes of CAP in ICU-admission, acute respiratory distress syndrome (ARDS) and 28-day mortality. According to the area under the curve (AUC) of the receiver operating characteristic (ROC) curves, the accuracies of prediction of the scoring systems were analyzed among CAP patients.    Results  The AUC values of the qSOFA, SOFA and CURB-65 scores for ICU-admission among CAP patients were 0.712 (95%CI: 0.678–0.745,  P  < 0.001), 0.744 (95%CI: 0.711–0.775,  P  < 0.001) and 0.705 (95%CI: 0.671–0.738,  P  < 0.001), respectively. For ARDS, the AUC values of the qSOFA, SOFA and CURB-65 scores were 0.730 (95%CI: 0.697–0.762,  P  < 0.001), 0.724 (95%CI: 0.690–0.756,  P  < 0.001) and 0.749 (95%CI: 0.716–0.780,  P  < 0.001), respectively. After 28 days of follow-up, the AUC values of the qSOFA, SOFA and CURB-65 scores for 28-day mortality were 0.602 (95%CI: 0.566–0.638,  P  < 0.001), 0.587 (95%CI: 0.551–0.623,  P  < 0.001) and 0.614 (95%CI: 0.577–0.649,  P  < 0.001) in turn. There were no statistical differences between qSOFA and SOFA scores for predicting ICU-admission (Z = 1.482,  P  = 0.138), ARDS (Z = 0.321,  P  = 0.748) and 28-day mortality (Z = 0.573,  P  = 0.567). Moreover, we found no differences to predict the ICU-admission (Z = 0.370,  P  = 0.712), ARDS (Z = 0.900,  P  = 0.368) and 28-day mortality (Z = 0.768,  P  = 0.442) using qSOFA or CURB-65 scores.    Conclusion  qSOFA was not inferior to SOFA or CURB-65 scores in predicting the ICU-admission, ARDS and 28-day mortality of patients presenting in the ED with CAP.

bmc infectious diseases

Efficacy of the quick sequential organ failure assessment for predicting clinical outcomes among community-acquired pneumonia patients presenting in the emergency department