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Background   Chlamydia trachomatis  and  Neisseria gonorrhoeae  are the two common transmissible pathogens from pregnant women to their neonates. Given the lack of routine screening and treatment of pregnant women in some areas, the possibility of transmission rises. This study seeks to determine the prevalence of  C. trachomatis  and  N. gonorrhoeae  in the pregnant women with no clinical symptoms and the vertical transmission rate to their neonates.    Methods  The study was conducted on endocervical and eye swab samples of 239 pregnant women and their neonates. Identification was based on PCR method.    Results  The prevalence rates of  C.trachomatis  in women and neonates were 37/239 (15.5%) and 28/239 (11.7%), and for  N. gonorrhoeae  3/239 (1.3%), 1/239 (0.4%), respectively. The vertical transmission rates to the neonates were 28/37(75.6%) for  C. trachomatis  and 1/3 for  N. gonorrhoeae .    Conclusions  In the areas with a high prevalence of chlamydial or gonococcal infections, and in the absence of screening and treatment of the pregnant women, ocular prophylaxis with antibiotics is suggested as a part of routine neonatal care program for the prevention of chlamydial and gonococcal ophthalmia.

bmc infectious diseases

Prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae infections among pregnant women and eye colonization of their neonates at birth time, Shiraz, Southern Iran