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Background  Physical activity programs (PAP) in patients with cardiovascular disease require evidence of cost-utility. To assess improvement in health-related quality of life (QoL) and reduction of health care consumption of patients following PAP, a randomized trial was used.    Methods  Patients from a health insurance company who had experienced coronary artery disease or moderate heart failure were invited to participate ( N  = 1891). Positive responders ( N  = 50) were randomly assigned to a progressively autonomous physical activity (PAPA) program or to a standard supervised physical activity (SPA) program. The SPA group had two supervised sessions per week over 5 months. PAPA group had one session per week and support to aid habit formation (written tips, exercise program, phone call). To measure health-related quality of life EQ-5D utility score were used, before intervention, 6 months (T6) and 1 year later. Health care costs were provided from reimbursement databases.    Results  Mobility, usual activities and discomfort improved significantly in both group (T6). One year later, EQ-5D utility score was improved in the PAPA group only. Total health care consumption in the intervention group decreased, from a mean of 4097 euros per year before intervention to 2877 euros per year after ( p  = 0.05), compared to a health care consumption of 4087 euros and 4180 euros per year, in the total population of patients ( N  = 1891) from the health insurance company. The incremental cost effectiveness ratio was 10,928 euros per QALYs.    Conclusion  A physical activity program is cost-effective in providing a better quality of life and reducing health care consumption in cardiovascular patients.    Trial registration   ISRCTN77313697 , retrospectively registered on 20 November 2015.    Electronic supplementary material  The online version of this article (10.1186/s12872-018-0973-3) contains supplementary material, which is available to authorized users.

bmc cardiovascular disorders

“As du Coeur” study: a randomized controlled trial on quality of life impact and cost effectiveness of a physical activity program in patients with cardiovascular disease