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Background  Chest compression is a decisive element of cardio-pulmonary resuscitation (CPR). By applying a mechanical CPR device, compression interruptions can be minimised. We examined the efficiency of manual and device-assisted resuscitation as well as the effects of cardiovascular risk factors on the outcome of resuscitation.    Methods  In our retrospective, randomised 3-year study the data of adult patients suffering non-traumatic, out-of-hospital, sudden cardiac death (SCD) were analysed ( n  = 287). The data were retrieved by processing case reports, Utstein sheets and acute coronary syndrome sheets. We compared the data of patients undergoing manual ( n  = 232) and device-assisted resuscitation (LUCAS-2,  n  = 55). The primary endpoint was the on-site restoration of spontaneous circulation (ROSC).    Results and conclusion  In 37% of the cases ROSC happened. With respect to ROSC an insignificantly more favourable tendency was demonstrated in the case of device-assisted resuscitation ( p  = 0.072). In the Lucas group, a higher success rate occurred even in the case of prolonged resuscitation. We found a better outcome in the Lucas group in the case of CPR started a longer time after the SCD ( p  < 0.05). A positive correlation was established between age and unsuccessful resuscitation (p = < 0.017;  r  = 0.125). An unfavourable correlation was observed between hypertension and the outcome of resuscitation ( p  = 0.018;  r  = 0.143). According to our results the presence of left ventricular hypertrophy poses 5.1-fold risk of unsuccessful CPR (CI: 4.97–5.29).  Advanced age and structural heart diseases can play a role in the genesis of SCD. Importantly, left ventricular hypertrophy and hypertension negatively affect survival.

Cardiovascular risk factors differently affect the survival of patients undergoing manual or mechanical resuscitation