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Background  Mob family proteins are conserved between animals, plants and fungi and are essential for the activation of NDR kinases that control crucial cellular processes like cytokinesis, proliferation and morphology.    Results  We identified a hypomorphic allele of  ChMOB2  in a random insertional mutant ( vir-88 ) of the hemibiotrophic ascomycete fungus  Colletotrichum higginsianum . The mutant is impaired in conidiation, host penetration and virulence on  Arabidopsis thaliana . ChMob2 binds to and co-localizes with the NDR/LATS kinase homolog ChCbk1. Mutants in the two potential ChCbk1 downstream targets  ChSSD1  and  ChACE2  show defects in pathogenicity. The genome of  C. higginsianum  encodes two more Mob proteins. While we could not detect any effect on pathogenicity in Δ Chmob3  mutants, ChMob1 is involved in conidiation, septae formation and virulence.    Conclusion  This study shows that ChMob2 binds to the conserved NDR/LATS Kinase ChCbk1 and plays an important role in pathogenicity of  Colletotrichum higginsianum  on  Arabidopsis thaliana .    Electronic supplementary material  The online version of this article (doi:10.1186/s12866-017-0932-7) contains supplementary material, which is available to authorized users.

ChMob2 binds to ChCbk1 and promotes virulence and conidiation of the fungal pathogen Colletotrichum higginsianum