English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Background  The Triatomine bug  Rhodnius prolixus  is a vector of  Trypanosoma cruzi , which causes the Chagas disease in Latin America.  R. prolixus  can also transfer transposable elements horizontally across a wide range of species. We have taken advantage of the availability of the 700 Mbp complete genome sequence of  R. prolixus  to study the dynamics of invasion and persistence of transposable elements in this species.    Results  Using both library-based and  de novo  methods of transposon detection, we found less than 6 % of transposable elements in the  R. prolixus  genome, a relatively low percentage compared to other insect genomes with a similar genome size. DNA transposons are surprisingly abundant and elements belonging to the  mariner  family are by far the most preponderant components of the mobile part of this genome with 11,015 m ariner  transposons that could be clustered in 89 groups (75 % of the mobilome). Our analysis allowed the detection of a new  mariner  clade in the  R. prolixus  genome, that we called  nosferatis . We demonstrated that a large diversity of m ariner  elements invaded the genome and expanded successfully over time  via  three main processes. (i) several families experienced recent and massive expansion, for example an explosive burst of a single  mariner  family led to the generation of more than 8000 copies. These recent expansion events explain the unusual prevalence of  mariner  transposons in the  R. prolixus  genome. Other families expanded  via  older bursts of transposition demonstrating the long lasting permissibility of  mariner  transposons in the  R. prolixus  genome. (ii) Many non-autonomous families generated by internal deletions were also identified. Interestingly, two non autonomous families were generated by atypical recombinations (5' part replacement with 3' part). (iii) at least 10 cases of horizontal transfers were found, supporting the idea that host/vector relationships played a pivotal role in the transmission and subsequent persistence of transposable elements in this genome.    Conclusion  These data provide a new insight into the evolution of transposons in the genomes of hematophagous insects and bring additional evidences that lateral exchanges of mobile genetics elements occur frequently in the  R. prolixus  genome.    Electronic supplementary material  The online version of this article (doi:10.1186/s12864-015-2060-9) contains supplementary material, which is available to authorized users.

Mariner transposons are sailing in the genome of the blood-sucking bug Rhodnius prolixus