English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Poly(ε-caprolactone) (PCL) nanofibers were prepared by electrospun, on which the  cis -diamminediiodoplatinum ( cis- DIDP) was loaded,  cis -DIDP@PCL, which effectively overcame  cis- DIDP from dissociation or premature interaction with other bimolecular groups. Meanwhile, the toxicity and cross-resistance of  cis -DIDP were reduced greatly. In vitro,  cis- DIDP released from the PCL nanofibers eradicated the tumor cells around twice times more than free  cis- DIDP, even better than cisplatin. Furthermore,  cis -DIDP@PCL could controllably release  cis- DIDP in different sustained-release solution based on our experiment.   Electronic supplementary material  The online version of this article (doi:10.1186/s11671-017-2092-y) contains supplementary material, which is available to authorized users.

Electrospun Poly(ε-caprolactone) Composite Nanofibers with Controlled Release of Cis-Diamminediiodoplatinum for a Higher Anticancer Activity