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Magnetic hyperthermia with the treating temperature range of 41–46 °C is an alternative therapy for cancer treatment. In this article, lanthanum strontium manganates (La 1− x  Sr  x  MnO 3 , 0.25 ≤ × ≤ 0.35) magnetic nanoparticles coated by hyaluronic acid (HA) which possesses the ability of targeting tumor cells were prepared by a simple hydrothermal method combined with a high-energy ball milling technique. The crystal structure, morphology, magnetic properties of the HA-coated magnetic nanoparticles (MNPs), and their heating ability under alternating magnetic field were investigated. It was found the HA-coated La 0.7 Sr 0.3 MnO 3 , with particle diameter of ~100 nm, Curie temperature of 45 °C at a concentration 6 mg/ml, gave the optimal induction heating results. The heating temperature saturates at 45.7 °C, and the ESAR is 5.7 × 10 −3  W/g · kHz · (kA/m 2 ) which is much higher than other reported results.   Electronic supplementary material  The online version of this article (doi:10.1186/s11671-016-1756-3) contains supplementary material, which is available to authorized users.

LSMO Nanoparticles Coated by Hyaluronic Acid for Magnetic Hyperthermia