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In order to consolidate the known human proteins interactions two tests were developed to measure the relative accuracy of the available interaction data. In addition, 6,580 interactions among 3,737 human proteins were recovered from Medline abstracts and combined with existing interaction data to obtain a network of 31,609 interactions among 7,748 human proteins, accurate to the same degree as the existing data sets.

Consolidating the set of known human protein-protein interactions in preparation for large-scale mapping of the human interactome.