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We commentary the recent study about combination of vasopressin and epinephrine versus epinephrine alone in out-of-hospital cardiopulmonray resuscitation. We analyse the results and methods of this study.We believe this study is more a demonstration of how important the time and timely application of vasopressors are, than evidence of insufficiency of combining vasopressin and epinephrine in the treatment of cardiac arrest.

Timeliness of administration of vasopressors in CPR