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Around 300,000 people in the United States experience an out-of-hospital cardiac arrest each year, and less than 10 % of them survive to hospital discharge [1]. Survival is only slightly better for in-hospital cardiac arrest [2]. While provision of basic measures like bystander cardiopulmonary resuscitation (CPR) or early defibrillation is consistently associated with better survival [3], the benefit of advanced life support (ALS) measures, such as ventilation with advanced airway and administration of drugs, has not been clearly demonstrated [4].

Is there still a place for vasopressors in the treatment of cardiac arrest?