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Yersinia ruckeri produces an antibacterial factor which inhibits the growth of a wide spectrum of Gram-negative and Gram-positive bacteria, though not other strains of Y. ruckeri. The antibacterial factor was produced at low temperatures (4–20°C), but not at 37°C. The activity was lost after treatment of the supernatant with chloroform, UV-light and after boiling of the supernatant. One did not succeed in obtaining the antibacterial factor in a sterile solution.

Antibacterial Spectrum and some other Characteristics of an Antimicrobial Factor produced by Yersinia Ruckeri