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The total body water (TBW) was determined, using a method with tritiated water. One litter of 11 piglets was used for the experiment comprising repeated deterimnations during the first 6 weeks of life. The mean TBW defined as the 1½ hours distribution volume of tritium after intraperitoneal injection was found to decrease gradually from 80.1 % of the body-weight at 1 day of age to 72.7 % at 19 days of age and then remained fairly constant. A simple distillation technique for recovering the water from plasma was used. Small variations between pigs of the same age were found. The variations in individual pigs from time to time and the results of duplicate determinations seem reasonable.

Volume of Distribution of Tritiated Water as a Measure of Total Body Water in Suckling Pigs