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Extracellular matrix proteins from embryonic mesenchyme have a normalizing effect on cancer cells  in vitro  and slow tumor growth  in vivo . This concept is suggestive of a new method for controlling the growth and spread of existing cancer cells  in situ  and indicates the possibility that extracellular proteins and/or embryonic mesenchymal fibroblasts may represent a fertile subject for study of new anti-cancer treatments.

A potential mechanism for extracellular matrix induction of breast cancer cell normality