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Neoadjuvant chemotherapy is used as the primary treatment for locally advanced breast cancer to reduce tumour size and protect against metastatic spread. Monitoring the response to chemotherapy is achieved mainly by clinical assessment, which may prove unsatisfactory. This proof-of-principle study is to determine if changes of size and texture in the elastogram can track tumour response.

Use of ultrasound elasticity imaging to monitor the response of a primary breast cancer to neoadjuvant chemotherapy in one patient in a pilot study