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Tamoxifen has an established role as the standard adjuvant therapy for early oestrogen-receptor-positive breast cancer. Aromatase inhibitors are now licensed for adjuvant treatment following 2 to 3 years of tamoxifen. This switch therapy offers both disease-free and modest overall survival advantages compared with 5 years of tamoxifen [1]. Greater Midlands Cancer Network guidelines based on NICE guidelines (2006) recommend switch therapy in patients who are not at low risk of recurrence [2]. There are no reports in the literature to indicate whether this is currently happening in clinical practice. We examined our own patient population to see if high-risk patients were being switched appropriately.

Stick or switch? Audit of the use of switch therapy from tamoxifen to an aromatase inhibitor in breast cancer