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CiCVVH has become standard treatment for on ICU with AKI. Though regional citrate anticoagulation for CRRT is recommended as first line therapy in the AKI guideline by the KDIGO Group, IHD is practised in many ICU patients with AKI. Evidence for superiority for one technique over the other remains equivocal, though there is increasing evidence for better renal function preservation in CVVH. However, there is also evidence for increased non-recovering of renal function in ICU patients with AKI who have hypomagnesemia.

Magnesium profiles in renal replacement therapy (rrt) on icu: citrate CVVH (CICVVH) vs. intermittent haemodialysis (IHD)