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During mechanical ventilation, reduction of expiratory pressure may trigger heterogeneous processes of derecruitment, collapse and overdistension of airspaces. However the relationship of such processes with precise regional location inside the lung has not been fully studied in vivo. Synchrotron Radiation Computed Tomography (SRCT) can provide in vivo regional images of the lung at resolutions higher than conventional CT.

Alveolar deflation dynamics before and after lung injury assessed by synchrotron radiation computed tomography