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Piperacilin-tazobactam (TZP) and meropenem (MER) are two extended-spectrum beta-lactams antibiotics (ATB) broadly used in intensive care units. We know that early and appropriate ATB treatment remains the most important intervention in septic patients, so optimization of ATB administration should be a priority.

Therapeutic drug monitoring of meropenem and piperacilin administered in continuous infusion. preliminary data