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Non-invasive ventilation (NIV) is the first line supportive treatment in case of acute hypercapnic respiratory failure (AHRF). NIV efficacy is continuously monitored using clinical parameters (respiratory frequency, use of accessory respiratory muscles). The assessment of NIV efficacy however usually requires repeated blood gas analysis after 30 or 60 minutes of treatment. A reliable non-invasive technique to continuously monitor PaC02 during NIV could simplify this evaluation and allow an earlier adaptation of ventilator settings.

intensive care medicine experimental

Relationship between transcutaneous C02 measurement and PAC02 during non invasive ventilation delivered because of hypercapnic acute respiratory failure