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Methods Nineteen patients were divided into high (Chigh group) and low pulmonary compliance (Clow group) groups based on their pulmonary compliance values (0.6 ml/[cmH2O·kg]). End-expiratory lung volumes (EELV) with different tidal volumes (VT at baseline and at 6, 8, 10 and 12 ml/kg predicted body weight [PBW]) were measured by nitrogen wash-in/washout. Lung strain was calculated as the ratio between tidal volume and EELV.

The effects of low tidal ventilation on lung strain correlate with pulmonary compliance