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Methods A retrospective, interventional, quasi-experimental study conducted in a medical-surgical ICU in two periods (4/1/2005 30/ 6/2009 and 4/1/2010 31/12/2012), including all patients admitted to our ICU. The intervention since September 2009 includes: proper hands hygiene, use of chlorhexidine, total aseptic measures during the central venous canalization, preferential use of subclavian vein and removal of useless central venous catheter (CVC). The main outcome variable was the rate of CLABSI (infections / 1000 days of catheter) before and after the intervention. Data were collected according ENVIN-HELICS study. Other variables included demographics data, primary diagnosis, APACHE II score, need of mechanical ventilation, use and duration of CVC, hospital mortality, and others. Statistical analysis: Descriptive, chi-square, t-Student, multivariate logistic regression analysis.

IMPACT OF A PREVENTION EDUCATIONAL PROGRAM OF CENTRAL LINE-ASSOCIATED BLOODSTREAM INFECTION IN A POLIVALENT ICU