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Background Mass poisoning with Datura alkaloids, present in contaminated buckwheat flour occurred in 2003 in Slovenia. A preliminary risk assessment for atropine and scopolamine in the flour was carried out. To obtain more accurate information, we performed a randomised, double-blind, placebocontrolled, crossover study in 20 healthy adult volunteers exposed to low doses of an atropine/scopolamine mixture as food contaminant.

Plasma levels of an atropine/scopolamine mixture following ingestion of low doses as food contaminant